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CBD circle graph - What is CBD
CBD chart - What is CBD

CBD Explained

Cannabidiol (CBD) is a cannabinoid. Cannabinoids are powerful compounds in the hemp plant, that aid in providing amazing relief for numerous health ailments. All cannabinoids, including CBD, work with your own endocannabinoid system (ECS), Endo (which means within the body) and Cannabinoid (the active ingredient that it acts upon). ECS includes Cannabinoid (CB) receptors, which regulate pain and inflammation. ECS controls coordination, movement, pain, emotions, mood, thoughts, appetite, our immune system and basically controls homeostasis.

“Hemp has a very low amount of the psychoactive constituent Δ9-tetrahydrocannabinol (THC) but higher quantities of CBD, which may offer a range of medicinal benefits without the cognitive effects and abuse potential associated with THC.” NIH

Important Cannabinoids include:

  • Cannabidiol (CBD)
  • Cannabinol (CBN)
  • Cannabigerol (CBG)
  • Cannabichromene (CBC)
  • Cannabidivarin (CBDv)
  • Cannabidiolic Acid (CBDA)
  • Naturally Present Terpenes

CBD is administered in a variety of mediums. Tinctures are administered sublingually, i.e. under the tongue and are absorbed very quickly into the tissue and blood stream via the mucous membranes in the mouth. Capsules are swallowed, absorbed through the gastrointestinal tract and metabolized by the liver. CBD that is vaporized or smoked is delivered directly from the lungs to the blood. A topical absorption of salves, lotions and creams is more about getting the CBD onto the affected skin, tissues and joints. The skin has many CB2 receptors that interact with cannabinoids and CBD has strong anti-inflammatory properties. Dosing amounts and time periods are varied per person and ailment. Start out with 1 dropper or 1 capsule a day to assess effectiveness and gradually increase as needed.

CBD may benefit a person or pet’s health in a variety of ways by providing natural pain relief and anti-inflammatory properties. The Journal of Experimental Medicine found that CBD significantly reduced chronic inflammation and pain in some mice and rats. The researchers suggested that the non-psychoactive compounds such as CBD, could provide a new treatment for chronic pain, quitting smoking and drug withdrawals. A study published in Addictive Behaviors found that smokers who used inhalers (vapes/e-juices) containing CBD smoked fewer cigarettes and reduced nicotine cravings.

CBD may be a promising treatment for people with opioid addition disorders. The researchers noted that CBD reduced some symptoms associated with substance use disorders. These included anxiety, mood-related symptoms, pain, and insomnia.

  1. “Opioid abuse is a significant global public health problem. Of the over million opiate-dependent subjects today, only less than a quarter of such individuals receive treatment. CBD’s selective effect on drug-seeking behavior was pronounced after 24 hrs and endured even two weeks after the last drug administration following short-term CBD exposure. The fact that drug craving is generally triggered by exposure to conditioned cues suggests that CBD might be an effective treatment for heroin craving, specially given its protracted impact on behavior. CBD has already been shown in various clinical studies to be well tolerated with a wide safety margin in human subjects. CBD thus represents a strong candidate for the development as a potential therapeutic agent in humans for opioid craving and relapse prevention.”
  2. “While CBD seems to have direct effects on addictive behaviors, its therapeutic potential could also be enhanced by several properties that contribute indirectly to addictive disorders. For example, its anti-anxiety properties are well known at doses of 300–600 mg and CBD seems to have antidepressant and anti-convulsant effects”.

After researching the safety and effectiveness of CBD oil for treating epilepsy, the FDA just approved the use of CBD (Epidiolex) as a therapy for two rare epileptic conditions and other neurological symptoms and disorders Researchers are studying the effects of CBD on various neuropsychiatric disorders. A 2014 review noted that CBD has anti-seizure properties and a low risk of side effects for people with epilepsy. Findings suggested that CBD may also treat many complications linked to epilepsy, such as neurodegeneration, neuronal injury, and psychiatric diseases. A Current Pharmaceutical Design published study found that CBD may produce effects similar to those of certain antipsychotic drugs, and that the compound may provide a safe and effective treatment for people with schizophrenia. Further research is necessary.

The British Journal of Clinical Pharmacology found evidence that CBD significantly helped to prevent the spread of cancer. The researchers also noted that the compound tends to suppress the growth of cancer cells, promote their destruction and has low levels of toxicity. CBD has been shown to be Antineoplastic (acting to prevent, inhibit or halt the development of a neoplasm aka a tumor).

Doctors often advise people with chronic anxiety to avoid cannabis as THC can trigger or amplify feelings of anxiousness and paranoia. No further definitive evidence links CBD to adverse affects. CBD also has a better safety profile compared to other cannabinoids, such as THC. For instance, high doses of CBD (up to 1500 mg/day) are well tolerated in animals and humans. In contrast to THC, CBD does not alter heart rate, blood pressure, or body temperature, does not induce catalepsy, nor alter psychomotor or psychological functions.

A Pediatric Anxiety and PTSD study concluded that CBD oil can be an effective compound to reduce anxiety and insomnia secondary to PTSD.

Type 1 diabetes results from inflammation that occurs when the immune system attacks cells in the pancreas. Research published in 2016 by Clinical Hemorheology and Microcirculation found that CBD may ease this inflammation in the pancreas. This may be the first step in finding a CBD-based treatment for type 1 diabetes. A paper presented in Lisbon, Portugal, suggested that CBD may reduce inflammation and protect against or delay the development of type 1 diabetes.

Acne treatment is another promising use for CBD (try Glenna’s CBD Best Oil Even & Clear to help alleviate acne & even skin tone). The condition is caused, in part, by inflammation and overworked sebaceous glands in the body. CBD is seen as a potent “universal” anti-acne agent, possessing a unique “triple anti-acne” profile. This is especially promising, because the currently available, most effective anti-acne agent, isotretinoin, is known to cause serious side effects. A 2014 study published by the Journal of Clinical Investigation found that CBD helps to lower the production of sebum that leads to acne, partly because of its anti-inflammatory effect on the body. Sebum is an oily substance, and overproduction can cause acne.

Journal of Alzheimer’s Disease found that CBD was able to prevent the development of social recognition deficit in participants. Meaning that CBD could help people in the early stages of Alzheimer’s by reducing the buildup of plaques and tangles, and therefore a viable potential as treatment options for Alzheimer’s disease. Turmeric and Extra Virgin Olive Oil have shown promise with easing Alzheimer’s disease impacts as well.

Many small-scale studies have looked into the safety of CBD in adults. They concluded that adults tend to tolerate a wide range of doses well. Researchers have found no significant side effects on the CNS (Central Nervous System), the vital signs, or mood, even among people who used high dosages.

A person can use CBD oil in different strengths and mediums to relieve various symptoms. We offer tinctures (sublingual), capsules, or as an ointment (salves and/or lotions) to be massaged into the skin. Triple Relief Salve & Serenity Lotion work great together on localized muscle, tendon and joint pain as well as an everyday lotion. Our Healing Salve & Lotion with Colloidal Silver (anti-bacterial) also work well on muscle, tendon and joint pain along with burns, cuts and other wounds.

Glenna’s CBD Best Oil full spectrum tinctures are available in the following strengths:

  • 300 mg (used by many for anxiety & pain)
  • 500 mg (also used by many for pain & insomnia)
  • 1000 mg
  • 1500 mg
  • 2000 mg

Glenna’s CBD Best Oil Water Soluble Concentrates can be mixed into different foods or drinks or taken with a pipette or dropper (1500mg or 3000mg isolate).

Recommended dosages vary between individuals, the concentration (mg) of the product and the health issue.

Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional.

All our products contain less than 0.3% THC or less. Copyright © 2016 Colorado's Brand Distributing DBA Glenna's CBD Best Oil - All Rights Reserved | 1892 Monroe Avenue, Rochester, NY 14618