I have started using the 500 mg tincture 2 times daily . It has Been a God send . I have severe chronic pain From rheumatoid arthritis and fibromyalgia . I am now taking less Narcotics Thanks to Glenna .i didn’t think anything would take away some of the pain . I now can go do my shopping without so much pain every week. I was just about to have my groceries delivered . But now I won’t . So I hope I will continue with my little less pain . It’s great !!!